Long-Distance Movement of Aspergillus nidulans Early Endosomes on Microtubule Tracks
نویسندگان
چکیده
منابع مشابه
Aspergillus RabBRab5 Integrates Acquisition of Degradative Identity with the Long Distance Movement of Early Endosomes
Aspergillus nidulans early endosomes display characteristic long-distance bidirectional motility. Simultaneous dual-channel acquisition showed that the two Rab5 paralogues RabB and RabA colocalize in these early endosomes and also in larger, immotile mature endosomes. However, RabB-GTP is the sole recruiter to endosomes of Vps34 PI3K (phosphatidylinositol-3-kinase) and the phosphatidylinositol-...
متن کاملIsolation of mip (microtubule-interacting protein) mutations of Aspergillus nidulans.
We identified four mutations in two previously undescribed loci involved in microtubule function in Aspergillus nidulans as extragenic suppressors of benA33, a heat-sensitive beta-tubulin mutation. Three of the four mutations map to a locus closely linked to riboB on linkage group VIII; we designated this locus mipA (for microtubule-interacting protein). We were not able to map the remaining su...
متن کاملEndosomes make tracks
arly endosomes may help to create their own short-range tracks, according to a report from Stéphane Gasman, Yannis Kalaidzidis, and Marino Zerial (Max Planck Institute, Dresden, Germany). The results also suggest parallels between membrane trafficking, signaling, and regulation of the cytoskeleton. Trafficking of early endosomes requires the small GTPase RhoD. Zerial’s group identified the firs...
متن کاملAspergillus nidulans
Light-dependent conidiation in the filamentous ascomycete, Aspergillus nidulans, is contingent on the allelic state of the velvet (veA) gene. Light dependence is abolished by a mutation in this gene (veAl) , which allows conidiation to occur in the absence of light. We have isolated and characterized six extragenic suppressors of veAl that restore the light-dependent conidiation phenotype. Alle...
متن کاملEffects of mitotic and tubulin mutations on microtubule architecture in actively growing protoplasts of Aspergillus nidulans
We used immunofluorescent microscopy to characterize microtubule (MT) architecture in wild-type and mutant protoplasts of Aspergillus nidulans at interphase and at mitosis. Because the visualization of MTs by immunofluorescence is technically difficult in intact hyphae of A. nidulans, we developed a method for removing the cell wall under conditions that do not perturb cell physiology, as evide...
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ژورنال
عنوان ژورنال: Traffic
سال: 2008
ISSN: 1398-9219
DOI: 10.1111/j.1600-0854.2008.00848.x